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Slay Demons With These Anime Inspired RPGs

4 Minute Read
Sep 20 2025
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Everyone seems to agree that Infinity Castle was great. So let’s all slay demons and have our own anime adventures with these TTRPGs!

Demon Slayer: Infinity Castle came out this past weekend, and everyone seems to be in agreement that it is awesome. But would we want to join the Demon Slayer Corps? Maybe not in real life… But at the TTRPG table is a different story!

The ven diagram of people who play tabletop RPGs and people who enjoy anime isn’t quite a circle, but there’s quite a bit of crossover between those two hobbies. And from slaying demons to sailors moon, there are a ton of genres and tropes to explore. If you, like me, have had an anime-inspired game in mind and ready to play for years, there are a couple of perfect game systems out there. So live your world-saving, demon-slaying anime dreams and jump into your perfect anime story isekai-style with these anime-themed RPG systems.

1. Big Eyes Small Mouth

BESM is the anime inspired tabletop RPG system. And it’s made to be good for any anime sub-genre. But can’t that be any kind of story? Because anime is a medium and not a genre? It is! This is a very open concept, generic style system. Think GURPs. Now think GURPs with big eyes. You’ve got it! There are a whole bunch of anime-specific trope, monsters, hero and villain types, etc. And BESM has spent four editions perfecting these.

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2. Mecha vs Kaiju

There are a few rule-sets that end up being utilized in many different RPG systems. It’s because they’re simple, fun, and generic enough that they can be easily re-skinned for many different settings with very little alteration to the core. FATE is one of the most popular of these rule-sets.

I’ve played a FATE-based Pokémon game (would recommend, very fun even if we did make the GM swear off GMing ever again with our antics). But I’m always looking for a different game experience next time and Mecha vs Kaiju just may be the way to go. You’re familiar with mechas. You’re familiar with kaijus. And you’re probably familiar with the idea of them punching each other thanks to things like Pacific Rim. I don’t know about you, but that sounds like a fantastic game to jump into for a few hours a week.

3. Anime 5E

Are you the kind of person who has played D&D and wants to expand out to other games, but aren’t sure where to dip your toe in the water? Anime 5E is a sort of happy middle ground. It’s definitely an anime game, but it uses a system a reimagining of “the fifth edition rules of the world’s most popular storytelling game.” Aiming for a happy medium between D&D and BESM, Anime 5E has all of the races, classes, skills, features, and everything else you expect to see on your character sheet. But in an anime setting.

4. Girl by Moonlight

Remember the 1999 Sailor Moon tabletop RPG? No? Honestly, that’s okay. It was from a time before tabletop RPGs were accessible and when tons and tons of rules were the goal for some reason. Also, it starts at $88 used on Amazon… Which made me consider selling the copy that I’ve had since 1999 for exactly two seconds. Luckily, there are better options now if you want to play that Sailor Moon inspired game, including Girl by Moonlight.

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But this isn’t a one-trick-pony sort of game, and it knows that there are different kinds of magical girls; it’s a diverse genre. Do you want to be a heroic Sailor Moon style story? Or a doomed Puella Magic Modoka Magica story? Perhaps you want something a little weirder and a little closer to the periphery of the genre like Paprika or Serial Experiments Lain? Personally, I want an absolutely bonkers Lain inspired campaign to play in and I need to find more people in that niche.

5. Yokai Hunters Society

Okay, we’ve talked a lot about anime games for any genre, and games for more specific genres. But we’re here today because of Demon Slayer, and we would be remis not to talk about any games that would work for a Demon Slayer inspired adventure. Enter, Yokai Hunters Society.

The year is 1889 (a little before Demon Slayers is set), yokai sightings and encounters have increased drastically, and you are joining a small society of people brave enough to fight what lurks in the shadows. This game could work equally well as a horror one-shot or a monster of the week campaign.

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